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Polynucleotides

 What are Polynucleotides?

Polynucleotides are often known as the “salmon sperm facial”. It is revolutionary treatment that offers longer lasting results than other treatments currently available.

  • Definition: Polynucleotides are long chains of nucleotides—the building blocks of DNA and RNA—typically purified from salmon or trout.
  • Scientific mechanism: Once injected into the skin, they stimulate fibroblasts, boosting collagen and elastin production. They also encourage cellular repair, improve hydration, reduce inflammation, and offer antioxidant benefits.

How They Work & Treatment Protocol

  1. Delivered via microdroplet injections.
  2. Typically, 2–4 sessions spaced 3–4 weeks apart, with maintenance every 6–12 months.
  3. Results generally appear in 4–8 weeks, with full effects at 12+ weeks.
Benefits of Profhilo

Benefits

Effect

Benefit

Collagen & Elastin Stim.

Firmer, tighter skin

Cellular Repair

Heals acne scars, improves tone & texture

Hydration

Plumper, smoother skin

Anti-inflammatory/Antioxidant

Reduces redness, calms skin

Suitable for delicate areas

Under-eyes, neck, décolletage, hands, scalp

Longevity & Downtime

  • Results Duration: 6–18 months, depending on protocol and maintenance
  • Downtime: Minimal—some redness, swelling, bruising for 24–48 hours

Cost

  • One session: £200–£500 depending on area
  • Package (e.g., 3 sessions): £550–£1,500+

Risks & Cautions

  • Generally well-tolerated, though side effects like bruising, swelling, temporary hardness, or allergic reactions can occur
  • A few users report persistent puffiness or discoloration under eyes

Real User Feedback

“I had three sessions… a few weeks after the third round… I looked much more glowy, revitalised and skin quality looked amazing.”